The Maintenance Phase: What Nobody Tells You About Surviving Between Breakthroughs
There is a moment in every biotech startup’s lifecycle where the champagne has been corked, the deck has been
The Discount Rate Is a Lie: Risk Isn’t a Constant in Biotech
There is a quiet confidence with which financial analysts deploy the discount rate—that tidy little variable in a discounted
Comfort Is a Liability: Why You Should Stay Paranoid (Just a Little)
There’s a certain temptation, once things start working, to exhale. The team is humming. The product is shipping. The
What to Do in a Down Market (Besides Complain About It)
Every founder eventually learns the same lesson: the market does not care about your milestones. It doesn’t care that
Buried in the Footnotes: Why It Pays to Pay Attention to Things Nobody Cares About
There’s a certain kind of career that doesn’t start with a big idea or a grand strategy. It
The Problem with Moonshots in Biotech: Big Promises, Bigger Problems
Moonshot thinking—a buzzword beloved by tech moguls and governments alike—has long dominated discussions in fields like AI and
The Joy of Working When Everyone Else is Gone
By the last man in the office
There are two types of people in the world: those who take holidays,
My Favourite Films Are About Financial Collapse—and They Teach More Than Most Business Schools
Ask most founders to list their favourite films and you’ll get a mix of productivity porn (The Social Network)
The Art of Business (and the Business of Art)
For an industry so obsessed with metrics, dashboards, and KPIs, business is surprisingly full of art. Not just metaphorically—though
The False Economy of Doing It All Yourself
There’s a particular kind of founder bravado—equal parts necessity and ego—that leads you to believe you can
