How Not to Give Up: On Motivation, Pivoting, and the Case for Antifragility
Startups rarely die all at once. They erode. Slowly. Through investor no’s, staff attrition, product-market ambiguity, and the general
When the Dream Doesn’t Deliver: On Closing, Pivoting, and Plan B
Founders are usually excellent at preparing for success. They build spreadsheets full of upside scenarios, draw hockey-stick revenue projections with
Why Biotech Startups Need Storytellers: The Cure for the Boring Deck Epidemic
Biotech startups are where some of the most groundbreaking ideas in science emerge. Yet their pitch decks often feel like
Decoding Investor Intent: It’s Not on the Website
Decoding Investor Intent: It’s Not on the Website
When it comes to raising capital, founders tend to be optimists—
How to Actually Find the Right Investors: A Field Guide for Biotech Founders
How to Actually Find the Right Investors: A Field Guide for Biotech Founders
In a previous post, I explained why
Just Asking for Money Is Not a Strategy
Somewhere between the lab bench and the pitch deck, a strange thing happens to many biotech founders. These are individuals
The Great European Biopharma Bottleneck: Capital Starved and Talent Stifled
European biopharma is a maddening paradox. It has the academic firepower to generate groundbreaking discoveries but lacks the financial machinery
First Principles: How to Think Like a Greek and Build Like a Founder
There’s an old saying in Silicon Valley: when in doubt, invoke physics. And so the term “first principles” has
Get Messy: Why Diving In Beats Waiting for Perfection
There’s a curious delusion that haunts modern professionals. The belief that before you start something—anything, really—you must
P-Hacking: The Fine Art of Massaging Numbers into Compliance
What Is a p-Value?
The p-value measures the probability of observing data as extreme as the actual results, assuming the
