Pie-Crust Promises: The $95 Billion Gap Between Biotech Biobucks and Reality (2023-2025)
Biotech deal announcements routinely trumpet eye-catching "biobucks" figures—billions promised in future milestone payments if all goes well.
Fund of the week: SWK Holdings
A Dallas-based specialty lender approaches a pivotal moment as it prepares to merge with Runway Growth Finance, marking the end of an era for one of healthcare credit's most specialized players.
Company of the week: Terray Therapeutics
Terray Therapeutics has assembled what may be the largest proprietary chemistry dataset in drug discovery—13+ billion target-molecule binding measurements, growing at 1 billion per quarter. The Los Angeles-based company has raised over $200 million.
The Volume Trap: Why Diagnostic Royalties Don't Compound
The Volume Trap: Why Diagnostic Royalties Don't Compound
Royalty financing has become a cornerstone of life sciences capital
Biotech ETFs Surge in 2025: The Complete Investor's Guide to a Sector Reborn
Biotech ETFs surge in 2025 as sector emerges from nuclear funding winter. XBI +37%, ARKG +43%, IBB +30%—all crushing the S&P 500. Big Pharma's $176B patent cliff drives M&A frenzy with 100%+ premiums. Fund flows turn positive for first time since 2021. Is the biotech winter finally over?
True Sale in Biotech Royalty Transactions: Meaning and Implications
Royalty financing can be structured as a “true sale” (outright transfer) or a secured loan backed by royalties. True sales often reduce bankruptcy risk and can bring legal/financial advantages; loan-like structures may leave the buyer exposed if the seller faces distress.
The Weekly Term Sheet (49)
The week's transactions tell a clear story: China-origin assets now command 32% of global licensing deal value, up
Structuring Around the Binary Risk: CVRs vs. Synthetic Royalty Swaps
Biotech valuation hinges on a small number of binary clinical events. A Phase 3 readout. An FDA approval letter. A
Fund of the week: Oberland Capital
In my November 25 post, I discussed "Royalties as a Credit Derivative," exploring how creative financing can extend
Company of the Week: Dayra Therapeutics
Dayra Therapeutics is a Toronto-based biotech company developing oral macrocyclic peptide drugs for immunological diseases. The company launched in November