17 min read

Fund of the week: Oberland Capital

Fund of the week: Oberland Capital

In my November 25 post, I discussed "Royalties as a Credit Derivative," exploring how creative financing can extend a biotech's runway without diluting equity. Oberland Capital is the real-world practitioner of that theory – a specialist fund that doesn't just bet on biotech outcomes, but engineers them through structured deals. In the current 2025 market, where the IPO window is highly selective and only the strongest data can crack open a listing, many biotechs are seeking alternative bridges to get them to a lucrative buyout or partnership.

M&A activity is heating up as big pharma hunts for late-stage assets, but emerging companies need cash to reach those inflection points.

Enter Oberland Capital: a private investment firm that provides "bridge" capital allowing biotechs to hit key milestones (like pivotal trial readouts or FDA approvals) without crushing their existing shareholders with dilution.

For example, Oberland recently struck a unique $600 million financing deal with Biohaven as it awaited an FDA approval – injecting life into the company at a critical juncture. Rather than a simple equity purchase, that deal was structured as a note purchase agreement (debt financing) with multiple tranches tied to Biohaven's milestones, precisely to carry the company through approval and toward commercialization.

This kind of tailored funding exemplifies how Oberland turns capital stacking theory into practice: providing cash now in exchange for a slice of future success, thereby building a synthetic bridge over the chasm between a cash-strapped present and a potentially profitable future.

Crucially, Oberland's money isn't "free" – it comes at a price – but the structure means the company's equity holders get to live to fight another day. In Biohaven's case, Oberland's support gave management the "flexibility to continue advancing [the] pipeline" and prepare for launch. Equity investors welcomed this lifeline: Biohaven's stock jumped ~10% on news of the Oberland funding, a positive reaction reflecting relief that the company secured needed capital without a massively dilutive stock offering.

This narrative – avoiding dilution while buying time to hit value-creating milestones – is at the core of Oberland's appeal. It's theory-into-practice for biotech financing: instead of trading public shares on binary events, Oberland structures private deals that manufacture a favorable outcome for all sides if the science delivers. In a market where many funds simply trade the volatility of clinical trial results, Oberland is the quiet engineer in the background, structuring the synthetic royalty streams and credit deals that turn those results into actual dollars and cents.

The Firm: From Paul Capital Spinout to $3.5 Billion Platform

Origins and Founding Team

The Oberland story begins at Paul Capital, where Jean-Pierre Naegeli and Andrew Rubinstein built and co-managed a healthcare royalty platform through the early 2010s. Both brought complementary backgrounds that would prove essential to Oberland's distinctive approach.

Jean-Pierre Naegeli, Managing Partner, spent nearly a decade at Johnson & Johnson, including five years leading principal investments at J&J Development Corporation, the pharmaceutical giant's strategic venture arm. His training included operational roles assessing healthcare technologies across all J&J divisions – pharmaceuticals, medical devices, and diagnostics.

This operational experience at one of the world's largest healthcare companies gave Naegeli deep insight into how products move from development through commercialization. Prior to J&J, he worked at Credit Suisse First Boston in investment banking. He holds an MBA from Yale School of Management and an engineering degree from ETH Zurich.

Andrew Rubinstein, Managing Partner, followed a different path – investment banking at Merrill Lynch's Financial Sponsors Group (focused on private equity clients), then serving as CEO of Microban International, a global antimicrobial licensing business where he led operations across 30 countries.

This CEO experience provided rare operational perspective for an investor. Before Paul Capital, he also worked in venture capital and merchant banking. Rubinstein holds a JD from NYU School of Law and an MBA from NYU Stern School of Business.

When they launched Oberland in 2013, their first key hire was Michael Bloom, a Paul Capital colleague who had previously consulted for healthcare firms including Health Advances and the Frankel Group. Bloom earned his MBA with honors from Wharton's Healthcare Management Program and remains a Partner today.

The founding trio brought William Clifford from Paul Capital as well – he had led strategy engagements for biotech and medical device clients at Health Advances and even worked at In-Q-Tel (the CIA's venture capital arm) during graduate school.

Fund Progression and Capital Raising

Oberland has demonstrated remarkable fundraising momentum, with each successive fund significantly larger than the last and all reaching hard caps ahead of schedule:

FundVintageTargetFinal CloseNotes
Fund I2015$350M$425M21% above target
Fund II2018$800MHit hard cap
Healthcare Solutions FundMay 2020$1.05BLate-stage clinical focus
Fund IIIOct 2022$1.2BClosed in ~6 months

The firm now manages over $3.5 billion in assets under management dedicated to healthcare royalty and credit opportunities. This consistent oversubscription reflects strong institutional demand for the asset class and confidence in Oberland's execution capabilities.

Current Team and Expertise

Oberland's approximately 20-25 employees combine scientific, operational, financial, and legal expertise rarely found in a single firm. The team boasts over 200 years of collective healthcare experience across science, investing, and business development.

NameTitleBackground
Jean-Pierre NaegeliManaging PartnerJ&J Development Corp (9 years), Credit Suisse First Boston
Andrew RubinsteinManaging PartnerMicroban International CEO, Merrill Lynch, Paul Capital
William CliffordPartnerHealth Advances, In-Q-Tel, Paul Capital
Michael BloomPartnerHealth Advances, Frankel Group, Wharton MBA
Cecilia GonzaloPartnerWarburg Pincus (12 years), Essex Woodlands, Goldman Sachs
Molly Scott, PhDPartnerYale PhD (microbiology), AstraZeneca
Brandon Holtrup, PhDPartnerYale PhD, AstraZeneca business development
Johannes Lauenstein, PhDPartnerCambridge PhD, BCG pharma consulting
Kristian WiggertGeneral CounselPartner at Covington & Burling, Morrison & Foerster
David DubinskyCFOManaging Director & CFO at Siguler Guff ($10B+ AUM)
Sarah SiberVice PresidentPfizer Corporate Development
Sean FillionVice PresidentSiemens Healthineers Strategy & M&A

This hybrid team can evaluate Phase 3 clinical data, assess regulatory pathways, model commercial scenarios, structure complex transactions, and monitor portfolio companies – capabilities that pure financial investors lack.

Strategy – The "Senior Security" Approach

Oberland Capital's strategy centers on being the senior, risk-mitigated capital provider in a biotech's capital stack. Unlike an equity fund (e.g., RA Capital) that takes on binary clinical trial risk in exchange for unlimited upside, Oberland focuses on later-stage assets – typically products in late Phase III, near approval, or even on the market – where the scientific risk is lower and commercial execution is the next step. By targeting commercial or near-commercial assets, Oberland is effectively lending against something tangible (or soon-to-be tangible) rather than a moonshot idea.

This is the essence of its "Senior Security" approach: Oberland structures its investments as senior secured obligations or revenue-linked royalties, positioning itself at the top of the capital structure with first claim on certain asset cash flows. The firm often insists on robust downside protection – think collateralization of IP or using bankruptcy-remote vehicles to hold the royalty rights – so that if the operating company fails, Oberland's claim on the product's revenue can survive.

Investment Parameters

ParameterDetails
Deal Size$50 million to $300+ million per transaction
Target StageLate Phase III, NDA/BLA filed, approved, or commercial
SectorsPharmaceuticals, biotechnology, medical devices, diagnostics
GeographyGlobal, with focus on US and Europe
Structure TypesRIPAs, royalty monetization, secured notes, hybrid instruments
Return ProfileCredit-like downside protection with equity-like upside participation

The Financing Toolkit

What truly sets Oberland apart is the flexibility and creativity of its deal structures. The firm doesn't just hand out loans or buy stock; it custom-crafts hybrid instruments that can include debt, royalties, and equity kickers all in one package.

Oberland's Financing Solutions:

Structure TypeDescriptionExample
Royalty MonetizationPurchase of existing royalty streamsAgenus $115M royalty transaction
Revenue Interest Purchase Agreement (RIPA)Synthetic royalty on future product salesImmunityBio $320M, Esperion $200M
Secured NotesSenior debt with milestone tranchesBiohaven $600M, Verastem $157.5M
Tiered Royalty InterestPercentage varies with sales levelsClearPoint Neuro structure
Project-Specific FinancingFunding tied to specific drug/indicationImpact Biomedicines fedratinib
Hybrid InstrumentsCombination of debt + royalty + equityClearPoint $110M (note + royalty + equity)

For example, in May 2025 Oberland provided ClearPoint Neuro with a structured financing that combined a secured note, a tiered royalty interest, and an equity purchase – a "broad suite" solution tailored to the company's needs.

The Limited Partner Base: Institutional Capital at Scale

Oberland's LP base spans public pension funds, corporate pensions, endowments, foundations, sovereign wealth funds, and family offices across the United States, Europe, and the Middle East. The firm has disclosed the following confirmed institutional investors:

Confirmed Limited Partners

InvestorTypeFund CommitmentAssets Managed
Public Safety Personnel Retirement System of Arizona (PSPRS)Public PensionFund I (2015), Fund III (2022)~$24 billion
Motion Picture Industry Pension Plan (MPIPHP)Industry PensionHealthcare Solutions Fund (2020)Multi-billion

PSPRS, managing approximately $24 billion in assets for Arizona firefighters, police officers, and corrections employees, committed to Oberland Capital Healthcare LP (Fund I) in April 2015. PSPRS has been recognized by Institutional Investor magazine as "Allocator of the Year" (2017), with CIO Mark Steed named "Innovator of the Year" (2023). The pension allocates 25% of its portfolio to "Contractual Income" – including private credit and royalty payments – emphasizing pharmaceutical investments and non-market-correlated returns.

MPIPHP, established in 1953 through collective bargaining between entertainment unions and employers, committed to Oberland's Healthcare Solutions Fund at its May 2020 close. The plan covers employees across 30+ entertainment industry unions and guilds.

Ropes & Gray LLP has served as legal counsel for Fund II onward, with Partner Marc Biamonte leading the team and tax partners Dan Kolb and Seth Piken supporting. No placement agents have been disclosed, suggesting the firm has relied primarily on direct investor relationships.

Complete Deal History: The Portfolio in Detail

Oberland's investment range spans $50 million to over $600 million per transaction. Below is a comprehensive review of the firm's disclosed investments with detailed terms where available.

Major Transactions Summary Table

CompanyDateAmountStructureKey Terms
BiohavenApr 2025$600MNote Purchase Agreement$250M at close, $150M at FDA approval, $200M optional; tiered royalties up to 10 years
ClearPoint NeuroMay 2025$110MNote + Royalty + Equity$33.5M at close; $3.5M equity at $12.69/share
VerastemJan 2025$157.5MNotes + Equity$75M at close; 6-year interest-only; 1% revenue participation
BillionToOneSep 2024$140MNon-dilutive notes$50M at close; retired $35M existing debt
ImmunityBioDec 2023$320MRIPA + Equity$210M at close; 3-10% tiered royalties; 195% cap
HumacyteMay 2023$160MRevenue-based + Equity$40M at close; milestone tranches; $10M equity option
Agenus2022$115MRoyalty MonetizationNon-dilutive royalty transaction
Zealand PharmaDec 2021$200MSecured Notes7-year term; 6.0% + LIBOR; repaid May 2023
Axogen2020$75MSecured Notes7-year term; 11.5% IRR target make-whole
EsperionJun 2019$200MRIPA2.5-7.5% royalties; 200-225% cap; repaid Jun 2024
NorthStar MedicalApr 2019$100MSecured Financing$75M at close; Mo-99 production expansion
Melinta2017$90MDebt + EquityBaxdela commercialization; company filed Ch.11 Dec 2019
Impact BiomedicinesOct 2017$90MStructured FinancingFedratinib development; acquired by Celgene Jan 2018
Axogen2014$28.55MLoan + Revenue Interest$25M loan + 3.75% revenue interest + $3.55M equity

Detailed Deal Breakdowns

Biohaven: $600 Million for Rare Disease (April 2025)

The firm's largest disclosed transaction is a $600 million Note Purchase Agreement with Biohaven (NYSE: BHVN), structured across three tranches:

TrancheAmountTrigger
Initial$250MFunded at closing
Second$150MFDA approval of troriluzole (company option)
ThirdUp to $200MMutual agreement for permitted strategic acquisitions

The return structure includes:

  • Regulatory approval milestone payments (payable quarterly through December 31, 2030)
  • Tiered single-digit royalty payments on global net sales of troriluzole
  • Maximum royalty term of 10 years
  • All payments capped at a multiple of amounts funded

Legal advisors: Covington & Burling LLP for Biohaven; Cooley LLP for Oberland.

ImmunityBio: Revenue Interest Plus Equity (December 2023)

Oberland committed up to $320 million to ImmunityBio (NASDAQ: IBRX) in a hybrid structure:

ComponentAmountTerms
RIPA$300M$200M at close; $100M at FDA approval
Equity$20M$10M at close (2.43M shares); $10M option

RIPA Royalty Terms:

StageRoyalty RateGeography
Pre-approval3-7% of net salesGlobal ex-China
Post-approval4.5-10% of net salesGlobal ex-China
Cap195% of investmentBy 12th anniversary

Critical structural element: Nant Capital agreed to subordinate its existing ~$505 million in notes to Oberland's senior position. Jefferies LLC advised ImmunityBio.

Verastem: Launching with Financial Strength (January 2025)

Oberland provided up to $157.5 million to Verastem Oncology:

ComponentAmountTerms
Notes$150M$75M at close; $75M at milestones
Equity$7.5M1.42M shares

Note Terms:

  • Six-year interest-only period with floating rates (floor and cap)
  • 1.0% revenue participation on first $100M of annual net sales
  • Proceeds repaid $42.7M Oxford Finance loan
  • PDUFA date: June 30, 2025 for avutometinib + defactinib

Esperion: The Full Transaction Lifecycle (2019-2024)

Oberland's $200 million RIPA with Esperion Therapeutics (NASDAQ: ESPR) demonstrates the complete lifecycle:

TrancheAmountTriggerDate
Initial$125MClosingJune 2019
Second$25MFDA approval of NEXLETOLMarch 2020
Third$50MSales milestoneApril 2021
Total Funded$200M
Repayment$343.75MEarly terminationJune 2024

Royalty Structure:

Sales LevelRoyalty RateStep-Down Conditions
Base2.5-7.5%
>$350M by Dec 20212.5% flatSales achievement
Full capital return by Dec 20240.4%Return + sales thresholds

The June 2024 repayment at $343.75 million – funded by a royalty sale to OMERS Life Sciences – represented approximately 172% return on the $200 million funded, consistent with the 200-225% cap.

How Revenue Interest Purchase Agreements Actually Work

Oberland's RIPAs represent a hybrid between traditional royalty and debt financing. Understanding the mechanical structure illuminates why these instruments appeal to both companies and investors.

RIPA Structure Comparison

FeatureTraditional DebtRIPAPerpetual Royalty
Payment timingFixed scheduleTied to salesTied to sales
Interest rateFixed or floatingN/A (% of revenue)N/A (% of revenue)
Principal repaymentRequiredVia royalty capNever
Upside participationNoneCappedUnlimited
Downside protectionCompany assetsSpecific product IPSpecific product IP
TermFixed maturityUntil cap reachedPerpetual or patent life

Key Structural Elements

Capital Deployment:

  • Companies receive large upfront payments (typically 50-80% of commitment)
  • Additional milestone tranches tied to regulatory approvals, clinical events, or sales thresholds
  • Front-loading provides immediate capital while aligning future payments with commercial success

Payment Mechanics:

  • Percentage of product net sales – typically single-digit royalties (2.5%-10%)
  • Rates may vary based on pre- versus post-approval status
  • Geographic scope defined (often global ex-China or specific territories)
  • Payments flow quarterly based on actual sales

Return Caps:

  • Unlike perpetual royalties, payments capped at predetermined multiple of investment (typically 175%-225%)
  • Once achieved, all rights revert to company
  • ImmunityBio: 195% by 12th anniversary
  • Esperion: 200-225%

Security Arrangements:

  • Senior security interests in specified assets
  • Royalties, license agreements, intellectual property, accounts receivable
  • Covenant packages restrict additional liens, indebtedness, M&A transactions, asset sales
  • Put options allow termination upon bankruptcy, material breach, or change of control

Illustrative RIPA Economics

ScenarioInvestmentRoyalty RateAnnual SalesAnnual PaymentYears to CapTotal Return
Base Case$200M5%$400M$20M10$200M (100%)
Upside$200M5%$800M$40M5$200M (100%)
Cap Applied$200M5%$1.2B$60M7.5$450M cap (225%)
Downside$200M5%$100M$5M40+Capped over time

Portfolio Outcomes: From $7 Billion Exits to Bankruptcy Navigations

Impact Biomedicines: The Signature Exit

The Impact Biomedicines investment represents Oberland's defining success story:

EventDateDetails
Impact founded2016Acquired fedratinib (JAK2 inhibitor) from Sanofi
Series A2016~$22M from Medicxi
Oberland financingOctober 2017~$90M structured financing
Celgene acquisition announcedJanuary 2018Up to $7 billion
Celgene upfrontJanuary 2018$1.1 billion
Regulatory milestonesPotentialUp to $1.25 billion
Sales milestonesPotentialUp to $4.5 billion (if >$5B annual)
FDA approval (Inrebic)August 2019Myelofibrosis indication

The timeline – just three months from Oberland investment to Celgene acquisition announcement – demonstrates exceptional returns on the structured financing.

Melinta Therapeutics:

  • Filed Chapter 11 in December 2019
  • Deerfield Management as primary secured creditor ($140M)
  • Deerfield exchanged claims for 100% equity of reorganized company (April 2020)
  • Remains listed on Oberland's portfolio page
  • Reflects structural challenges in antibiotics sector despite FDA approvals

Invitae:

  • Filed Chapter 11 in February 2024
  • Approximately $1.5 billion in total debt (primarily SoftBank's $1.2B convertible)
  • Labcorp acquired through bankruptcy court-supervised sale (August 2024)
  • Oberland's recovery undisclosed; secured positioning typically provides better outcomes

Current Portfolio Status Summary

CompanyStatusKey Update
BiohavenActiveAwaiting FDA decision on troriluzole
ImmunityBioActiveAnktiva FDA approved April 2024; commercializing
VerastemActivePDUFA date June 30, 2025
ClearPoint NeuroActiveExpanding cell/gene therapy delivery platform
BillionToOneActiveIPO'd November 2025 at $60/share
HumacyteActiveAdvancing toward FDA BLA filing
EsperionRepaid$343.75M repayment June 2024
Zealand PharmaRepaidEarly termination May 2023
Impact BiomedicinesExitedCelgene acquisition January 2018

The Competitive Landscape: Positioning Against $20 Billion Giants

The life sciences royalty and structured finance market has expanded significantly, with approximately $29.4 billion in transactions from 2020-2024 – more than the entire 2015-2019 period. The 2025 market is annualizing at $5.42 billion with average deal sizes of $226 million.

Healthcare Royalty & Credit Market Participants

FirmAUM/Market CapPrimary FocusTypical Deal SizeKey Differentiator
Royalty Pharma (RPRX)~$20B market capPure royalty acquisition$100M-$2B+Largest, oldest player (1996)
HealthCare Royalty Partners (KKR)~$3B AUMRoyalties + credit$50M-$500MKKR acquired July 2025
Blackstone Life Sciences$12B+ deployedStrategic partnerships$100M-$750MPharma mega-partnerships
BioPharma Credit PLC (LSE: BPCR)~$1.1BSenior secured debt$50M-$350MLondon-listed, public liquidity
Oberland Capital~$3.5B AUMFlexible hybrid structures$50M-$600MStructural creativity, mid-market focus
DRI Healthcare (TSX: DHT.UN)$3B+ deployedRoyalty acquisitions$50M-$180MCanadian-listed income trust
XOMA Royalty (NASDAQ: XOMA)120+ assetsEarly-stage royalties$5M-$30MPhase 1/2 focus, milestone-based
OrbiMed$17B platformMulti-strategy$50M-$300MRoyalty & Credit Fund V: $1.86B

The KKR/HCRx Combination: A Formidable Competitor

In July 2025, KKR announced strategic acquisition of HealthCare Royalty Partners (HCRx), marking significant sector consolidation. Per KKR: "Royalty and royalty-related debt financing represents less than 5% of total biopharma capital needs today and remains largely underpenetrated."

HCRx MetricsValue
AUM~$3 billion
Total deployed since 2006$7+ billion
Products funded110+
New ownerKKR (majority stake)
Strategic rationaleGlobal Atlantic insurance capital access

This KKR backing provides HCRx with dramatically expanded capital markets capabilities, creating Oberland's most direct competitor.

Oberland's Competitive Positioning

DimensionOberland Advantage
Structural FlexibilityOffers royalties, RIPAs, secured notes, project finance, hybrid instruments vs. competitors' narrower approaches
Sector BreadthIncludes medical devices and diagnostics; Royalty Pharma is biopharma-only
Mid-Market Focus$50-300M sweet spot falls below Royalty Pharma's minimum but remains meaningful for growth companies
Scientific ExpertiseMultiple PhDs, former pharma executives enable direct clinical data evaluation
Speed and CreativitySmaller team enables faster structuring of customized transactions

Why the 2024-2025 Market Makes Alternative Financing Essential

The biotech financing environment creates structural demand for Oberland's capital:

The Cash Runway Crisis

Metric20212024Source
Biotechs with <1 year cash31%37%+EY
Biotechs with <2 years cash~40%50%+EY
Biotechs with 5+ years cash24%18%EY

IPO Market Dynamics

YearBiopharma IPOsCapital RaisedTrading Performance
2023~30$5.1BMixed
202450$8.52B8 of 30 above offering price
2025 (Nov YTD)~10Pace slowing

The Patent Cliff Driving M&A

DrugCompanyRevenue at RiskPatent Expiration
KeytrudaMerck$29B (40% of pharma rev)2028
OpdivoBMS$9B+2028
EliquisBMS/Pfizer$12B+2026-2028
Total at risk through 2030$200-400B

This patent cliff drives aggressive M&A – but acquirers want de-risked, clinical-stage assets. Oberland financing helps companies reach those inflection points.

Biotech Sector Valuation

The XBI biotech ETF and broader healthcare sector trade at approximately 30% discount to the broader market – one of the most significant de-ratings in 35 years. This valuation compression makes equity raises extremely expensive for companies, increasing demand for non-dilutive alternatives.

Inside the Deal Mechanics: IP Collateralization and Bankruptcy Remoteness

Oberland's legal structures employ sophisticated techniques from project finance and securitization:

Security Interest Framework

Asset ClassProtection Mechanism
PatentsUSPTO recordation, security interest filings
RoyaltiesAssignment or security interest in payment streams
License AgreementsConsent rights, assignment provisions
Accounts ReceivableBlanket lien, proceeds capture
After-Acquired PropertyAutomatic capture clauses

Bankruptcy-Remote Structures

Industry-standard approaches isolate financial risk:

ElementPurpose
Special Purpose Vehicle (SPV)Holds royalty rights separate from operating company
Independent DirectorRequired consent for bankruptcy filing
True-Sale OpinionConfirms asset transfer (not merely pledge)
Non-Petition CovenantCreditors agree not to force SPV bankruptcy
Limited Purpose ProvisionsSPV can only engage in specified activities

Subordination and Intercreditor Arrangements

The ImmunityBio deal illustrates subordination mechanics:

  • Nant Capital's existing ~$505M in promissory notes subordinated to Oberland
  • Intercreditor agreement defines priority of claims
  • Oberland's RIPA receives first claim on product revenue

Fund Formation

CounselFundsKey Partners
Ropes & Gray LLPFund II, Solutions, Fund IIIMarc Biamonte, Dan Kolb, Seth Piken

Portfolio Transaction Counsel

FirmRoleExample Transactions
Cooley LLPOberland counselBiohaven, ClearPoint Neuro
Covington & Burling LLPCompany counselBiohaven, ClearPoint Neuro, Humacyte
Wilson SonsiniCompany counselImmunityBio
Jefferies LLCFinancial advisorImmunityBio

Red Team vs. Blue Team: Evaluating Oberland's Model

Blue Team (Optimist) – Why Oberland's Strategy Shines

Non-Dilutive Lifeline: From a biotech company's perspective, Oberland is a savior that provides vital runway without diluting ownership. As Oberland's own partners emphasize, they pride themselves on offering "an attractive, non-dilutive source of capital" to help companies advance important new therapies. In practical terms, this means a company can fund trials or product launches and still have the full upside if those efforts succeed – equity holders' percentage ownership remains intact.

Aligned with Milestones – Boosting Confidence: Oberland's financings are typically aligned with the company's milestones (e.g., tranches tied to FDA approval or sales targets), which sends a positive signal to the market. Investors often welcome Oberland's involvement as a validation of an asset's quality and the company's prospects. For example, when Biohaven announced Oberland's $600 million funding deal, shares jumped ~10% – a sign that shareholders appreciated the endorsement.

Predictable Returns for Investors (LPs): From the perspective of Oberland's own investors (the pensions, endowments, etc.), the model offers attractive, more predictable returns relative to traditional biotech venture capital. By focusing on products with real revenue potential and structuring deals to have first claim on cash flows, Oberland generates steady royalty or interest income even if equity markets are volatile. The firm's exclusive focus on serious, high-need diseases also means they are backing products that, if successful, will likely have durable demand.

Red Team (Skeptic) – Risks and Caveats to Consider

High Cost of Capital: The flip side of "non-dilutive" is that Oberland's money is expensive. A skeptical view is that these deals, while avoiding immediate dilution, siphon off a significant portion of future revenues, which can hamstring the company later. For instance, Biohaven agreed to pay "tiered single-digit royalties on global net sales for up to 10 years" as part of Oberland's deal. That means if troriluzole succeeds, a meaningful chunk of its sales for the next decade goes to Oberland.

Complexity and Covenants – Strings Attached: Oberland's financings come with heavy structuring and covenants, which can be a double-edged sword. In a best-case scenario, those structures protect both parties – but if things start to go wrong for the company, the strict terms might accelerate the downfall. The red team would point out that having senior secured debt and royalty obligations increases the fixed burden on a biotech. If the clinical trial fails or approval is delayed, the company could find itself owing money it cannot pay.

Sharing the Upside and Impact on Exit: Even in successful outcomes, a red-team analyst might argue that Oberland's involvement crimps some upside that would otherwise accrue to shareholders or an acquirer. Because the royalty/notes are usually capped at a multiple, if a drug turns into a mega-blockbuster, the company will eventually buy out Oberland by reaching that cap – but until then, the payments act like a drag on cash flow.

Summary: Neither Good nor Bad, but Powerful

ConsiderationBlue Team ViewRed Team View
DilutionAvoided entirelyFuture earnings diluted via royalties
Cost of CapitalAcceptable for runwayExpensive over product life
CovenantsAppropriate protectionRestrictive in distress
Exit ImpactBridge to higher valuationAcquirer must buy out obligation
DownsideSenior security protects OberlandCompany still bears execution risk

Conclusion: The Architect of Biotech Capital Stacks

Oberland Capital's model is a sophisticated tool in the biotech financing toolkit – neither inherently good nor bad, but powerful. Blue team optimists see it as a brilliant way to fund innovation without killing the equity goose that may later lay the golden eggs, leveraging structured finance to everyone's benefit. Red team skeptics caution that the golden eggs don't come free – some of the gold is pre-sold to Oberland, and if the eggs don't hatch, you're left with a heavy obligation.

As we spotlight Oberland this week, it's clear that they exemplify the "capital stacking" approach: stacking debt, royalty, and equity layers to build a bridge for biotechs to cross the valley of death. Whether that bridge leads to a blockbuster payday or adds weight on a shaky foundation depends on the situation. But one thing is for sure – in 2025's biotech landscape, Oberland Capital has become a key architect of deals, quietly shaping the fate of drugs and companies from behind the scenes.

For institutional investors seeking healthcare exposure with income-like characteristics, the firm has delivered consistent fund raises and portfolio execution across market cycles. For biotech companies facing capital constraints but holding promising clinical assets, Oberland offers a differentiated value proposition: patient capital, flexible structures, deep domain expertise, and alignment through milestone-based funding and capped returns.

In a sector where more than a third of public companies face existential cash crunches, Oberland Capital has positioned itself as an essential – and increasingly sought-after – source of alternative financing. And for that, they've earned a reputation as one of the most innovative and important funding partners in the industry, turning financial theory into practice one structured deal at a time.

Disclaimer: I am not a lawyer or financial adviser. This article does not constitute investment advice, legal advice, or financial advice of any kind. All information presented here is derived from publicly available sources including SEC filings, press releases, and industry reports. Details of specific transactions may have changed since publication. Readers should conduct their own due diligence and consult with qualified legal and financial professionals before making any investment or business decisions.