Latest

25
Nov
Royalties as a Credit Derivative: Modeling Default Risk in a High-Yield Environment

Royalties as a Credit Derivative: Modeling Default Risk in a High-Yield Environment

A synthetic royalty stream can be viewed not just as an asset purchase but as a complex credit derivative. In
23 min read
24
Nov
The Capital Stacking Quagmire: Sequencing Royalty Deals in a Public Biotech

The Capital Stacking Quagmire: Sequencing Royalty Deals in a Public Biotech

Introduction In today's tough biotech funding climate, many public biotechs have resorted to creative financing combos to stay
20 min read
23
Nov
The Weekly Term Sheet (47)

The Weekly Term Sheet (47)

Biotech and Healthcare Transactions Report: November 17-21, 2025 Abbott's $21 billion Exact Sciences acquisition dominated a busy week
24 min read
22
Nov
Jefferies Week London 2025 – A City Buzzing with Healthcare Deals and Innovation

Jefferies Week London 2025 – A City Buzzing with Healthcare Deals and Innovation

London has just wrapped up the Jefferies Global Healthcare Conference 2025, now firmly established as Europe’s largest healthcare investment
8 min read
21
Nov
Company of the week: SanegeneBio

Company of the week: SanegeneBio

SanegeneBio is a venture-backed biotechnology company founded in 2021, focused on developing RNA interference (RNAi) therapeutics for cardiometabolic and immunological
13 min read
20
Nov
Royalty Finance Without the Ornament: How Charities, Lawyers and Biotech Veterans Actually Use It

Royalty Finance Without the Ornament: How Charities, Lawyers and Biotech Veterans Actually Use It

We held our first royalty-financing event in London during the Jefferies Healthcare Conference, a meeting better known for quick negotiations
5 min read
19
Nov
Cross-Border Pharmaceutical Royalty Transactions

Cross-Border Pharmaceutical Royalty Transactions

Introduction The pharmaceutical royalty market has become increasingly sophisticated, with specialized funds and institutional investors acquiring rights to future royalty
23 min read
18
Nov
Biotech Liquidation Market Enters Consolidation Phase Amid Historic Sector Distress

Biotech Liquidation Market Enters Consolidation Phase Amid Historic Sector Distress

The biotech liquidation market showed signs of maturation during September-November 2025, with established players pausing acquisition activity while market distress
12 min read
17
Nov
The Promise and Perils of Royalty-Financed Platform Trials: Can Wall Street Finally Cure ALS?

The Promise and Perils of Royalty-Financed Platform Trials: Can Wall Street Finally Cure ALS?

A new financing model proposes to bridge biotech's "valley of death" by combining adaptive platform trials
12 min read
16
Nov
The Weekly Term Sheet (46)

The Weekly Term Sheet (46)

The biotech sector experienced one of its most intense dealmaking periods of 2025 during November 10-15, with over $25 billion
21 min read