Latest

18
Aug
Private equity moves deeper into biotech royalties as funding crisis intensifies

Private equity moves deeper into biotech royalties as funding crisis intensifies

Private equity firms deployed $5.42 billion into biotech and pharmaceutical royalty transactions through 2025, marking a 7% increase from
7 min read
17
Aug
The weekly term sheet (33)

The weekly term sheet (33)

Pharma & biotech deals heat up with $5B+ in transactions The week of August 11-15, 2025 witnessed a striking bifurcation
8 min read
16
Aug
Space: the final formulation frontier

Space: the final formulation frontier

These are the voyages of a new class of pharmaceutical pioneers. Their five-year mission: to explore strange crystallization conditions, to
14 min read
15
Aug
Company of the week: Arrakis navigates the undruggable desert

Company of the week: Arrakis navigates the undruggable desert

Finding the spice in RNA's vast landscape Arrakis Therapeutics has positioned itself as a pioneer in RNA-targeted small
14 min read
14
Aug
Fund of the week: RTW Investments

Fund of the week: RTW Investments

RTW Investments has transformed from a specialized healthcare hedge fund into a $9.8 billion life sciences investment platform that
18 min read
13
Aug
Advanced Private Equity Deal Structuring in Biotech & Pharma (U.S. & Europe)

Advanced Private Equity Deal Structuring in Biotech & Pharma (U.S. & Europe)

Risk-Adjusted NPV (rNPV) in Biotech Valuation The rNPV Formula rNPV = Σ [P(success) × NPV(success) + P(fail) × NPV(fail)] Explicitly
32 min read
12
Aug
Regulatory Sandboxes for AI in Drug Development and Clinical Trials

Regulatory Sandboxes for AI in Drug Development and Clinical Trials

Regulator Depth/Specificity of AI Sandbox (focus on AI in drug development) Scope of AI Experimentation (breadth of permitted AI
50 min read
11
Aug
Special Purpose Acquisition Companies in Healthcare and Biotech: A Mid-2025 Market Appraisal

Special Purpose Acquisition Companies in Healthcare and Biotech: A Mid-2025 Market Appraisal

The landscape for Special Purpose Acquisition Companies (SPACs) within the healthcare and biotechnology sectors in mid-2025 presents a complex, dual
21 min read
10
Aug
The weekly term sheet (32)

The weekly term sheet (32)

Global pharmaceutical and biotech deals remain subdued during August week The week of August 4-9, 2025 marked an unusually quiet
7 min read
09
Aug
The great AI medicine show

The great AI medicine show

In the late 19th century, traveling medicine shows peddled cure-all elixirs with flamboyant claims. Today’s equivalent in biotech is
28 min read