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Royalties on Antibody-Drug Conjugates: The Linker-Payload Patent Problem and Who Owns the Royalty When Three Parties Each Contributed a Component

The antibody-drug conjugate has a structural feature that makes it uniquely problematic from an intellectual property standpoint: it is, by design, a composite of three distinct technologies developed by three communities of scientists who largely did not know each other. The antibody came from one tradition, the cytotoxic payload from
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